CD4 Count Trends

CD4 Count Trends in Sub-Saharan Africa

WHO Treat All guidelines expanded

Notes:

Regional and country level aggregate data are generated from regional patient-level databases, using the IeDEA Data Exchange Standard (DES). Data reflects the situation at clinics contributing data to IeDEA, which may not be nationally representative.
All ART-naïve patients newly enrolling in HIV care from 2010 to present at a site participating in IeDEA were eligible for inclusion if they had at least 15 months between enrollment and database close or transfer to another site of care. The following patients were excluded: patients with incomplete data related to age, sex, and site of enrollment and patients with evidence of ART initiation prior to the date of enrollment.

Definitions:

Enrollment in HIV care: Enrollment in HIV care at a site participating in the IeDEA consortium, based on the date of enrollment recorded in the database
Enrollment CD4 count: CD4 count measure within 3 months (+/-) of the date of enrollment, or no more than 30 days after ART initiation among those initiating treatment within 3 months of care entry. For patients with >1 CD4 count, CD4 measure closest to enrollment date is used.
Median CD4 count at enrollment: Median CD4 count among patients with a recorded CD4 count measure within 3 months of enrollment and no more than 30 days after ART initiation. For patients with >1 CD4 count within the ascertainment window, CD4 measure closest to enrollment date is used.

Visit the Measures and Methodology page for information about data methods, sources, definitions, and suppression rules.

Notes:

No data suppression rules are applied to the clinic and country-level data that are accessible through password-protected clinic user accounts. Caution is advised when interpreting data visualizations and trends for small numbers of patients.
Country-level data are aggregated from patient-level databases at clinics participating in IeDEA, using the IeDEA Data Exchange Standard (DES). These clinics are not nationally representative. Aggregated country-level data that are accessed through password-protected clinic user accounts may differ from data displayed on the public version of the Treat All Dashboard because of differences in exclusion criteria and suppression rules.
All ART-naïve patients newly enrolling in HIV care since 2010 at clinics that participate in IeDEA were eligible for inclusion if they were 5 years and older with at least 3 months of between enrollment and database close or transfer to another site of care, or at least 30 days between ART initiation and database close or transfer to another site of care among those initiating treatment within 3 months of enrollment. The following patients were excluded: patients with incomplete data related to age, sex, and site of enrollment and patients with evidence of ART initiation prior to the date of enrollment.

Definitions:

Enrollment in HIV care: Enrollment in HIV care at a site participating in the IeDEA consortium, based on the date of enrollment recorded in the database.
Enrollment CD4 count: CD4 count measure within 3 months (+/-) of the date of enrollment, and no more than 30 days after ART initiation among those initiating treatment within 3 months of care entry. For patients with >1 CD4 count, CD4 measure closest to enrollment date is used.
Median CD4 count at enrollment: Median CD4 count among patients with a recorded CD4 count measure within 3 months of enrollment and no more than 30 days after ART initiation. For patients with >1 CD4 count within the ascertainment window, CD4 measure closest to enrollment date is used.

Visit the Measures and Methodology page for information about data methods, sources, definitions, and suppression rules.